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Genomics, MS Courses

The following are courses in the Genomics, MS program.

Required Courses

GN 701: Intro to Genomics

3 Credits
This course explores the history of genetics and genomics. Family history is discussed as a vital part of a genetic risk assessment and tool for evaluation of inheritance patterns and penetrance of disease. The course concludes with a review of the epigenetic influences on health and epidemiologic approaches to evaluate health and disease and applications in genomics.

GN 702: Genetic Concepts Testing and Translation to Healthcare

3 Credits
The course will serve as the basis for the healthcare professional to integrate genetics and genomics into personalized healthcare. The course will provide the clinician a review of sources of information available to the student in genomic healthcare for clinical management and therapeutic applications.

GN 703: Ethical, Legal, Social Issues in Genomics and Pharmacogenomics

3 Credits
This course exposes students to the ethical, legal, and social issues surrounding genetic testing and genetic testing available in a direct‐to‐consumer approach. Approaches to engage individuals as partners in healthcare will be explored in the course, as will the expanding applications of pharmacogenomics.

GN 704: Cancer Genomics and Applications of Genomics in Health and Disease

3 Credits
This course exposes the student to the role of genetics and genomics in cancer diagnosis prognosis and treatment. Future directions of genetics and genomics with comprehensive genome/exome/transcriptome sequencing in oncology, polygenic risk scores cell-free DNA, and genome-wide and phenome-wide association studies are addressed. Genomic technologies and ̀computational approaches that are driving advances to manage health and treat disease will be reviewed.

GN 710: Principles of Genetics

3 Credits
This course provides students an introduction to genetics with a focus on transmission and molecular genetics. The course makes use of bioinformatics to explore gene function and covers pertinent applications of bioinformatics and genetics to modern biological problems. Topics include chromosome structure and replication, variations and extensions of transmission genetics, genetic linkage and mapping, regulation of gene expression, epigenetics, genetic mutations, genetics of cancer, and the principles of genetic engineering.

GN 715: Chromosomes and Human Disease

3 Credits
This course exposes students to the role of chromosomes in human disease and seeks to familiarize students with the field of cytogenetics, the study of chromosomes, including the relationship between chromosomal abnormalities and human disease. Topics covered include cytogenetic methodology, aneuploidy, chromosome rearrangements, chromosomes and cancer, chromosome breakage syndromes, and fragile sites on human chromosomes.

GN 720: Molecular Basis of Human Inherited Disease

3 Credits
This course seeks to familiarize students with the molecular basis of diseases of human genetics and applications to modern research. This course provides a comprehensive examination of the principles of human inheritance, in the context of both normal human variation and human disease. The course explores mechanisms of gene regulation and introduces students to recombinant DNA and protein expression techniques.

GN 725: Clinical Applications of Genetics and Genomics

3 Credits
The course focuses on the genetic basis of disease and cytogenic analysis for applications to clinical care. Diagnostic molecular approaches and the clinical translation of genetic and genomic health information in a personalized healthcare environment are explored.

GN 730: Evolutionary Analysis

3 Credits
This course introduces students to evolutionary science and population genetics subject matter on the importance of four factors: selection, migration, mutation, and genetic drift. Students evaluate human evolution and impact on health.

GN 735: Human Population Genetics

3 Credits
Sequencing of the human genome has led to an emergence of population genomics. The course covers the basics of population genomic analysis from SNP data to the key analyses that may be required to successfully analyze a population genetic data set. Population genetics topics will also include computational methods and machine learning techniques.

GN 740: Public Health Genetics

3 Credits
Public health ensures the basic conditions required for individual and population health are present. The role of genetics in public health is evolving, as is the understanding of genetic disease. This course provides students with advances in genetic knowledge and technology that could be used to prevent disease and improve public health.

GN 745: Genomic Statistics and Research

3 Credits
This course provides students an introduction to the statistical approaches used in solving problems in genetic epidemiology. Methodological expositions and practical guidelines for software selections are included. Topics include molecular genetics and Mendelian description principles, genetic markers and distances, model-based and model-free population and family-based (genome wide) association studies, and association analysis using haplotypes.